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br Results br Discussion Two different lineages of BAs
2018-10-20
Results Discussion Two different lineages of BAs have been known. Classical BAs are derived from Myf-5 expressing common progenitors for myoblasts and BAs (Seale et al., 2008). The myoblastic precursors originate from the mesenchymal stem guanylyl cyclase (MSCs). PRDM16 is crucially involved
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br Experimental Procedures br Acknowledgments br Introductio
2018-10-20
Experimental Procedures Acknowledgments Introduction The human palatine tonsil is part of a circular collection of specialized B-lymphoid structures located in the oropharynx at the opening of the aerodigestive tract (Figure 1A). The outer surface of the human palatine tonsil is lined with
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Recently several studies have suggested that peripheral bloo
2018-10-20
Recently, several studies have suggested that peripheral blood mononuclear hcv protease inhibitors (PBMCs) are a promising resource for generating iPSCs because most of these cells do not undergo TCR rearrangement (Loh et al., 2010; Mack et al., 2011; Seki et al., 2010). However, PBMCs are composed
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The NT formation and NESC to RGPCs
2018-10-20
The NT formation and “NESC-to-RGPCs” transition at the onset of neurogenesis are two fundamental events in the early developing diacylglycerol kinase (Götz and Huttner, 2005). However, the developmental regulations are unclear due to being hard to definitely control the two stages. In this study, th
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In the present study we
2018-10-20
In the present study, we generated an Eva1a knockout (KO) mouse to study the physiological role of EVA1A in vivo. The analysis of Eva1a KO embryos and isolated NSCs revealed the function of EVA1A in self-renewal and neuronal differentiation of NSCs. Our study highlighted a previously unknown role of
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Neuroanatomical studies indicate that DARPP neurons could be
2018-10-20
Neuroanatomical studies indicate that DARPP32+ neurons could be divided into two populations: one that constructs a direct pathway and another that constructs an indirect pathway. DARPP32+ neurons in the direct pathway express DRD1 and are located in the striosome. On the other hand, those in the in
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Numerous morphogenetic events are explained by the cell surf
2018-10-20
Numerous morphogenetic events are explained by the cell surface tension model. In equilibrium, surface tension is minimized via coordinated forces generated by cell surface tension and actomyosin-mediated cortical tension, resulting in cell sorting and self-organization (Beysens et al., 2000; Heisen
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The in vitro process of spontaneous attachment
2018-10-20
The in vitro process of spontaneous attachment and spreading of the cysts, Dispase-mediated detachment, and subsequent floating culture achieves an outcome similar to that in in vivo optic cup invagination from optic vesicles. A process of embryonic body formation, attachment, manual dissection or m
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At a global level the analysis of
2018-10-20
At a global level, the analysis of DNA-methylation profiles provides important insights into molecular and cell growth characteristics of PSC that would otherwise be difficult to identify. Reprogramming-associated variations in X-linked CpG methylation is of particular interest because of the comple
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Further analysis of subtype specification of hiNSCs
2018-10-20
Further analysis of subtype specification of hiNSCs indicated that after 2 weeks in culture, hiNSCs spontaneously differentiate into mostly glutamatergic and GABAergic neurons, and do not express high levels of the dopaminergic neuron marker TH. While these subtypes were obtained from spontaneous di
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br Results br Discussion Human HLCs derived from pluripotent
2018-10-20
Results Discussion Human HLCs derived from pluripotent stem Erlotinib Hydrochloride are permissive to infection by hepatotropic viruses, including HCV and HBV. Interestingly, the SEC14L2 gene, an essential host factor for supporting the replication of wild-type, unadapted HCV genomes, was ind
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Hello world!
2018-07-29
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