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Introduction Pulmonary vein isolation PVI is an
2019-06-11
Introduction Pulmonary vein isolation (PVI) is an established strategy of paroxysmal atrial fibrillation (PAF) ablation [1–3]. Radiofrequency catheters have been the standard for AF ablation; however, PVI using balloon-based ablation has been increasingly adopted by electrophysiology laboratories a
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energy metabolism Qu dicen las fechas en
2019-06-11
¿Qué dicen las fechas en que se ha flexibilizado la posición de ambas partes? Veamos una cita elocuente sobre la situación internacional en la década de los años setenta del siglo pasado, marco en el que se mejoraron las relaciones entre Washington y La Habana, bajo el gobierno de James Carter. Por
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Reframing non communicable diseases NCDs to
2019-06-11
Reframing non-communicable diseases (NCDs) to “spur a sense of urgency” and “focus attention on effective system-wide interventions” makes sense. With almost three-quarters of NCD deaths now occurring in low-income and middle-income countries (LMICs), the increasing burden of NCDs already has severe
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br Water the main component of Earth
2019-06-10
Water—the main component of Earth\'s ecosystems—concentrates some of the most worrying global concerns that have emerged during the Anthropocene. When it comes to health considered at a planetary level, the challenges related to water can be sorted into five main categories: pollution, access to w
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br In the cluster randomised controlled trial by Marcel
2019-06-10
In the cluster randomised controlled trial by Marcel Yotebieng and colleagues (August, 2015) the addition of Step 10 of the UNICEF Baby Friendly Hospital Initiative (BFHI)—that is, the provision of additional support for breastfeeding—did not enhance the effects of steps 1–9, and may even have les
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br Ablation strategies from targeted to homogenization The
2019-06-10
Ablation strategies – from targeted to homogenization The techniques and principles originally developed in postinfarction scar have been translated and applied to patients with various etiologies of fibrosis and confluent scar including Chagasic cardiomyopathy, nonischemic cardiomyopathy, arrhyt
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The electrophysiological mechanisms underlying high frequenc
2019-06-10
The electrophysiological mechanisms underlying high frequency activity observed in the PLA during SRAF could be reentry (rotor) or focal discharges (triggered activity). To discriminate between these mechanisms, we perfused ryanodine (10–40μM) or caffeine (5mM) to abolish calcium overload-mediated t
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The so called driver hypothesis has been
2019-06-10
The so-called driver order KN-93 hydrochloride has been posited in the recent years. Optical mapping studies in isolated sheep hearts have suggested that at least some cases of AF can be maintained by high-frequency reentrant sources (rotors), usually located in the posterior LA, which result in sp
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Introduction The heart beat provides the mechanical force fo
2019-06-10
Introduction The heart beat provides the mechanical force for the pumping of oxygenated blood to, and deoxygenated blood away from, the peripheral tissues [1]. This depends critically on the orderly activation and recovery of electrical excitation through the myocardium. Disruptions of this can lea
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Brasil ha sido el principal pa s de origen
2019-06-10
Brasil ha sido el principal país de origen de las importaciones argentinas hasta el punto que en 2011 tales importaciones del vecino sumaron más de 21 000 millones de dólares. Es cierto que la compra de productos brasileños fue disminuyendo desde 2003, que representaba 34% del total de las importaci
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El tenor de aquella declaratoria se
2019-06-10
El tenor de aquella declaratoria se escribió con estas palabras: De este modo, y al margen de otras consideraciones que pudieran hacerse al respecto, para el caso que nos ocupa es importante significar que la iniciativa mexicana acabó tapiando las puertas de la onu Histone Compound Library la Españ
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br Methods br Discussion We
2019-06-10
Methods Discussion We observed a significantly lower than expected Day +100 TRM. Other NMAT studies [4,5] have shown similar findings, although 60% of our trial LY2584702 had high risk disease per the CIBMTR classification. In this and other studies, late TRM and disease progression remains p
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br Discussion To our knowledge we report
2019-06-10
Discussion To our knowledge, we report for the first time t(8;21) acute myeloid leukemia presenting as severe aplastic anemia. t(8;21)(q22;q22) is present in 5–10% of all AMLs, and includes variety of subtypes with varying pathology, and clinical presentations, ranging from circulating blast in p
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Adequate nutritional support for pregnant women is an
2019-06-10
Adequate nutritional support for pregnant women is an important issue, not only to help such women maintain peak health and performance, but also as it indirectly affects fetal growth and the minimization of adverse fetal outcome risks. Among those nutritional components that are integral to this su
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Conflict of interest br Introduction
2019-06-10
Conflict of interest Introduction Nifekalant hydrochloride was first approved by the Japanese Ministry of Health, Labour and Welfare in 1999 and is now used as a first-line antiarrhythmic drug for refractory ventricular tachyarrhythmias in the country [1]. Nifekalant is a class III antiarrhythmi
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