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Any web based literature search
2020-07-28
Any web-based literature search shows how the field is rapidly expanding. This is, not in small part, due to the “ENOR initiative” launched by Dr Iuliano and Dr Lizard in 2010 (). The European Network for Oxysterol Research (ENOR), via regular meetings and symposia, has helped moving the field forwa
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With respect to the duration
2020-07-28
With respect to the duration of acid-etching, few studies have shown that ceramic etching with a 5% HF during for 2–3 min is sufficient to dissolve the glassy phase [32], increasing roughness and creating a surface more favourable to bonding. Similarly, a previous study [33] showed that 10% hydroflu
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In most of the angiosperms
2020-07-28
In most of the angiosperms, sexual reproduction requires a process called double fertilization where the specialized cell division called meiosis produces haploid gametes combine to form diploid (2n) embryo. In toremifene citrate to this, apomixis, naturally occurs in at least 400 plant families (C
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While linear sequences are important they
2020-07-28
While linear sequences are important, they must be viewed with some caution. One noteworthy example is the C1 domains which have attracted some interest as they are known to bind phorbol esters and DAG (reviewed in (Das and Rahman, 2014)). In this, it was not unreasonable to suspect that one or more
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br Conflict statement br Introduction Prostate cancer
2020-07-28
Conflict statement Introduction Prostate cancer (PCa) is the second most frequently diagnosed cancer and the second leading cause of cancer death in men after lung cancer [1], [2]. The incidence and mortality rate of prostate cancer are significantly higher in developed countries especially th
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An important strength of our study is
2020-07-28
An important strength of our study is the use of an elastic net regression model to select the variable and construct the model, which performed ideally in terms of both predictive accuracy and sparsity for the high-dimensional datasets [16]. As a result, the apparent predictive effect of multiple c
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Strikingly FG binding pockets from the N and C terminal
2020-07-28
Strikingly, FG-binding pockets from the N- and C-terminal region of CRM1 bind to FG motifs on Nup214 that are separated by a rather short stretch of amino acids. This is possible because, in the context of an export complex, the CRM1 termini are in close proximity, allowing simultaneous binding of t
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br Results br Discussion Rat pups emitted a low
2020-07-28
Results Discussion Rat pups emitted a low number of vocalizations at 37 °C and maintained normal skin temperature. In contrast, when rat pups were isolated at 24 °C, a temperature significantly lower than skin temperature, calls were emitted approximately 11-times more frequently than pups at
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Large yellow croaker Larimichthys crocea are widely cultured
2020-07-28
Large yellow croaker (Larimichthys crocea) are widely cultured in China but have inferior meat texture compared with wild fish. This result results from excess lipid deposition in the muscle, which reduces mechanical strength (Thakur et al., 2003). The liver is the central of lipid metabolism and st
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Notochord is a transient structure
2020-07-28
Notochord is a transient structure differentiating at early stage during embryogenesis that is at the origin of vertebral bodies in all vertebrates. In zebrafish, it is composed of vacuolated Ponesimod surrounded by a unique ECM structure improperly called notochordal BM. As in chicken and amphibian
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br Acknowledgements br Introduction Water and electrolytes c
2020-07-28
Acknowledgements Introduction Water and electrolytes constitute an integral part of all living things, and osmi governing their movements play important roles in a wide variety of physiological and/or pathophysiological processes. Given the importance of channel proteins in cancer cell prolif
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litter basket Association between ESR mutation status and ty
2020-07-27
Association between ESR1 mutation status and type of endocrine therapy is an interesting subject. Longstanding endocrine therapy could provoke the occurrence of ER mutation according to Darwinian theory. One of the key findings of this work is the high prevalence of ER mutation in patients treated w
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br Material and methods br Results br
2020-07-27
Material and methods Results Discussion We previously reported that type I collagen is a potent inducer of linear invadosomes (Juin et al., 2012) and that DDR1 is required for their formation and matrix degradation activity (Juin et al., 2014) (Di Martino et al., 2015). As TGF-β1 was descri
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thiostrepton br Materials and methods br
2020-07-27
Materials and methods Results Discussion Although no increase in DAPK activity was detected at early time points associated with neuronal apoptosis, it is possible that the spread of apoptosis through the thiostrepton following HI is not synchronized enough to yield a large, consistent flu
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The notion that a small subset of inducible cellular transcr
2020-07-27
The notion that a small subset of inducible cellular transcripts, encoding immunological important factors, is translocated across the nuclear envelope by the karyopherin CRM1 is gaining support from various recent studies. For example, experimental evidence has been provided demonstrating that the
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