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molar calculator Liver metabolic programming begins in utero
2021-03-03
Liver metabolic programming begins in utero. Aiming to find a reason for the decreased lipid catabolism enzyme expression observed in fetuses and offspring from SFD rats, we studied the effect of leptin on liver catabolism in fetuses from control and SFD rats. Livers from control fetuses responded t
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Errors are detected by comparing the output
2021-03-03
Errors are detected by comparing the output data against an error free reference. After error detection, the process is restarted so that only one error is accounted. The susceptibility is inferred by the ratio between injected events and detected errors: = 100×errors÷events%. Error rates are obtai
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Asteroids can provide an abundant supply
2021-03-03
Asteroids can provide an abundant supply of other resources, such as carbon, nitrogen, or calcium compounds, but will only be useful once the space economy is sufficiently developed to provide economically interesting uses for them. Others, such as titanium or aluminium, also exist in asteroids, but
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Several studies highlighted the potential of EOCs to
2021-03-03
Several studies highlighted the potential of EOCs to promote adverse effects on aquatic organisms. It was reported the toxicity of BPA to invertebrates and fish, and the effect of lipophilicity on toxicity was analyzed (Mathieu-Denoncourt et al., 2016). There was reported the effects of PPCPs on aqu
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br In some but not all human
2021-03-03
In some, but not all, human vessels, a small population of ETB (usually Ezetimibe with atherosclerotic lesions did not show any increase. In agreement, in experimental medicine studies in both heart failure patients and volunteer controls, selective ETA antagonism (BQ123) caused the expected poten
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Introduction Maintenance of genome integrity
2021-03-03
Introduction Maintenance of genome integrity is essential for life, and faithful DNA replication and repair ensure this. One of the most important parameters for DNA maintenance is the regulation of optimal concentrations of the four 5′-deoxyribonucleoside-triphosphates (dNTPs) the precursors for D
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br Expression of DNMTs during testicular development In most
2021-03-03
Expression of DNMTs during testicular development In most multicellular organisms, male and female germ cells are the origin of development of an organism, and they provide inheritance of genetic and epigenetic information across the generations. Primordial germ cells (PGCs) derive from a subset
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All DGKs have at least two cysteine rich regions
2021-03-03
All DGKs have at least two cysteine-rich regions homologous to the C1A and C1B motifs of PKCs [26]. In theory, these domains may bind DAG, perhaps localizing DGKs to where DAG accumulates. However, no DGK C1 domain has so far been conclusively shown to bind DAG. In fact, structural predictions sugge
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br Materials and methods br
2021-03-03
Materials and methods Results Discussion In the past decade, GWAS have attempted to identify genetic variants that confer risk for many human diseases, whose inherited components remain unexplained (Manolio et al., 2009). In a few cases risk variants identified by GWAS have paved the way fo
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br Experimental procedures br Results Fluorescence attributa
2021-03-02
Experimental procedures Results Fluorescence attributable to GnRH-eGFP neurons was observed through the diagonal band of Broca, to the POA of the hypothalamus in GnRH-eGFP transgenic rats for all groups as described previously (Kato et al., 2003, Tada et al., 2013). Discussion The mEPSCs w
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br Acknowledgments The research in this
2021-03-02
Acknowledgments The research in this study was supported by grants from CMHS, UAE University and Qatar University. The authors gratefully acknowledge Dr. R Lukas (Barrow Neurological Institute, Phoenix, AZ, USA) for SH-EP1 pmsf stably expressing the human α7 nACh and human α4β2 nACh receptor and
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Concholepas concholepas our model species for
2021-03-02
Concholepas concholepas, our model species for this study, is a marine gastropod found along the Chilean coast that has become commercially important [25], [26], [27]. Until now, the main focus of immunology related to C. concholepas is the production of a novel hemocyanin that has been useful for t
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Multiple sequence alignment of the
2021-03-02
Multiple sequence alignment of the proteins in the DGAT1 sub-family shows that there are about 41 conserved amino AZ505 ditrifluoroacetate mg residues distributed over seven sequence motifs [74]. Unlike DGAT2, a large number of DGAT1 residues, including a majority of the conserved residues, are fou
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Patients with a tumor of cm
2021-03-02
Patients with a tumor of 4 cm or greater were more likely to have lymph node or tumor metastasis (Fisher’s test p = 0.0001 and 0.0003, respectively). In this smaller patient group a significant correlation between higher DAPK-1 mRNA Rebastinib synthesis in tumor and normal tissue in tumor-free patie
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Findings from this study also indicate that
2021-03-02
Findings from this study also indicate that DAPK regulated BimEL expression during OGD as DAPK shRNA transfection inhibited OGD-induced increase of BimEL. A previous study shows that Bim is found in ER compartment in stressed Rimonabant but not in normal cells, indicating translocation of Bim durin
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